IB Biology SL & HL · 2025 Syllabus

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IB Biology

Spaced repetition flashcards, daily games, and 1,500+ key terms — covering every topic on the 2025 IB Biology syllabus. Free, forever.

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1,500+
IB Biology key terms
32
Syllabus topics covered
4
Revision games
100%
Free

How it works

Built for how your brain actually learns

Rereading notes is the least effective revision strategy. Cramly uses active recall and spaced repetition — the techniques backed by the most evidence in learning science.

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Spaced Repetition Flashcards

Cards you struggle with come back more often. Cards you know well appear less. The algorithm prioritises exactly what you need to review.

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Biowordle — Daily Word Game

Guess the IB Biology term in 6 tries. A new word every day, drawn from the full syllabus. Great for 5 minutes of active recall on your commute.

Recall — Name the Terms

Type as many IB Biology keywords as you can before the timer runs out. Each correct term adds 6 seconds. Race the leaderboard.

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Progress Tracking

See exactly which topics you're weakest in, track your daily streak, and watch your mastery score grow across the full syllabus.

All IB Biology Topics

Cramly covers every topic from the 2025 IB Biology syllabus — both SL and HL. Topics marked HL are Higher Level only.

A1.1

Water

Hydrogen bonding, cohesion, adhesion, specific heat capacity, surface tension and the properties of water as a solvent.

A1.2

Nucleic Acids

DNA and RNA structure, nucleotides, complementary base pairing, the double helix, replication, transcription, and translation.

A2.1 · HL

Origins of Cells

The Miller-Urey experiment, protocells, LUCA, the reducing atmosphere, ribozymes, and the origins of life on Earth.

A2.2

Cell Structure

Prokaryotic and eukaryotic cells, organelles, electron microscopy, the cytoskeleton, endosymbiosis, and cell theory.

A2.3 · HL

Viruses

Viral structure, lytic and lysogenic cycles, HIV, coronavirus, bacteriophages, and the role of viruses in evolution.

A3.1

Diversity of Organisms

Species concepts, karyotypes, dichotomous keys, continuous and discrete variation, speciation, and whole genome sequencing.

A3.2 · HL

Classification and Cladistics

Cladograms, parsimony, binomial nomenclature, the domains of life, and how molecular data informs classification.

A4.1

Evolution and Natural Selection

Darwin and Lamarck, heritable variation, natural selection, allopatric and sympatric speciation, and adaptive radiation.

A4.2

Conservation of Biodiversity

Species richness, ecosystem diversity, in situ and ex situ conservation, seed banks, rewilding, and the biodiversity crisis.

B1.1

Carbohydrates and Lipids

Monosaccharides, disaccharides, polysaccharides, triglycerides, phospholipids, steroids, condensation and hydrolysis reactions.

B1.2

Proteins

Amino acids, primary to quaternary structure, denaturation, fibrous vs globular proteins, haemoglobin, insulin, collagen.

B2.1

Membranes and Membrane Transport

The fluid mosaic model, phospholipid bilayer, diffusion, osmosis, active transport, endocytosis, and exocytosis.

B2.2

Organelles and Compartmentalisation

Mitochondria, chloroplasts, the Golgi apparatus, lysosomes, ribosomes, and how compartmentalisation enables metabolism.

B2.3

Cell Specialisation

Stem cells, differentiation, totipotency, pluripotency, erythrocytes, neurons, epithelial cells, and the stem cell niche.

B3.1

Gas Exchange

Lung structure, ventilation, haemoglobin and oxygen affinity, the Bohr shift, stomata, gills, and the oxygen dissociation curve.

B3.2

Transport in Animals and Plants

The cardiac cycle, blood vessels, lymph, xylem, phloem, transpiration, the pressure-flow hypothesis, and coronary heart disease.

B3.3 · HL

Muscles and Motility

The sliding filament theory, sarcomere structure, actin and myosin, antagonistic muscles, synovial joints, and endoskeletons.

B4.1

Adaptation to Environment

Biomes, abiotic factors, range of tolerance, limiting factors, and adaptations to deserts, tundra, tropical forests, and coral reefs.

B4.2

Ecological Niches

Fundamental and realised niches, competitive exclusion, herbivory, predation, saprotrophic nutrition, and mixotrophs.

C1.1

Enzymes and Metabolism

Active site, induced fit, activation energy, competitive and non-competitive inhibition, feedback inhibition, and immobilised enzymes.

C1.2

Cell Respiration

Glycolysis, the link reaction, the Krebs cycle, the electron transport chain, chemiosmosis, ATP synthase, and anaerobic pathways.

C1.3

Photosynthesis

Photosystems I and II, the light-dependent reactions, the Calvin cycle, carbon fixation, RuBP, Rubisco, and chromatography.

C2.1 · HL

Chemical Signalling

Hormones, receptors, G-proteins, signal transduction, cyclic AMP, the menstrual cycle, and cell-to-cell communication.

C2.2

Neural Signalling

Resting and action potentials, synapses, neurotransmitters, myelination, saltatory conduction, and the effects of drugs on the nervous system.

C3.1

Integration of Body Systems

The reflex arc, the enteric nervous system, plant hormones (auxin, ethylene, cytokinin), circadian rhythms, and the brain.

C3.2

Defence Against Disease

Innate and adaptive immunity, B and T lymphocytes, antibodies, antigens, vaccines, blood clotting, and antibiotic resistance.

C4.1

Populations and Communities

Carrying capacity, sigmoid growth curves, the Lincoln index, interspecific and intraspecific competition, mutualism, and parasitism.

C4.2

Transfers of Energy and Matter

Trophic levels, energy pyramids, the carbon cycle, carbon sources and sinks, decomposers, and the Keeling curve.

D1.1

DNA Replication

Helicase, DNA polymerase, leading and lagging strands, Okazaki fragments, PCR, gel electrophoresis, and DNA profiling.

D1.2

Protein Synthesis

Transcription, translation, codons, anticodons, tRNA, rRNA, mRNA, splicing, the genetic code, and post-translational modification.

D1.3

Mutations and Gene Editing

Point mutations, frameshift mutations, mutagens, CRISPR-Cas9, gene knockouts, and the ethics of gene editing.

D2.1

Cell and Nuclear Division

The cell cycle, mitosis, meiosis, crossing over, non-disjunction, Down syndrome, cyclins, checkpoints, and cancer.

D2.2

Gene Expression

Transcription factors, enhancers, epigenetic tags, methylation, histones, the difference between genotype and phenotype.

D2.3

Water Potential

Osmosis, water potential, solute potential, pressure potential, plasmolysis, crenation, and turgor pressure in cells.

D3.1

Reproduction

Spermatogenesis, oogenesis, the menstrual and ovarian cycles, fertilisation, IVF, seed dispersal, and flower structure.

D3.2

Inheritance

Mendel's laws, Punnett grids, codominance, sex linkage, polygenic inheritance, dihybrid crosses, and chi-square tests.

D3.3

Homeostasis

Blood glucose regulation, thermoregulation, osmoregulation, the kidney and nephron, ADH, insulin, glucagon, and negative feedback.

D4.1

Natural Selection

Allele frequency, Hardy-Weinberg equilibrium, directional, stabilising and disruptive selection, and sexual selection.

D4.2

Ecosystem Stability

Ecological succession, keystone species, biomagnification, eutrophication, microplastics, and tipping points.

D4.3

Climate Change

The albedo effect, ocean acidification, coral bleaching, permafrost, carbon sequestration, and polar habitat loss.

Key vocabulary

Essential IB Biology Terms

Knowing definitions precisely is essential for IB Biology mark schemes. Here's a sample of the terms covered in Cramly across all topics — the full list has 1,500+.

Active Transport
Allele Frequency
Anaphase
Anticodon
Apoptosis
ATP Synthase
Bilayer
Bohr Shift
Calvin Cycle
Carrying Capacity
Chemiosmosis
Chromatid
Cladogram
Codominance
Competitive Inhibitor
Complementary Base Pairing
Corpus Luteum
CRISPR
Crossing Over
Cyclin
Denaturation
Depolarization
Dichotomous Key
Differentiation
Diploid
DNA Polymerase
Electron Transport Chain
Endosymbiosis
Epigenetic
Erythrocyte
Eutrophication
Exon
Fluid Mosaic Model
Frameshift Mutation
Genetic Drift
Glycolysis
Guard Cell
Hardy-Weinberg
Helicase
Homologous Chromosome
Induced Fit
Innate Immunity
Intron
Keystone Species
Krebs Cycle
Lignin
Lincoln Index
Loop of Henle
Lymphocyte
Meiosis
Meristem
Methylation
Mitosis
Monoclonal Antibodies
mRNA
Mycorrhizae
Myosin
Negative Feedback
Non-Disjunction
Nucleosome
Okazaki Fragment
Oncogene
Osmoregulation
Oxygen Dissociation Curve
PCR
Phloem
Phosphodiester Bond
Photolysis
Photosystem II
Plasmolysis
Pluripotent
Prophase
Proximal Convoluted Tubule
Reproductive Isolation
Resting Potential
Ribozyme
RuBP
Rubisco
Saltatory Conduction
Sarcomere
Selective Permeability
Semi-Conservative
Signal Transduction
Sliding Filament Theory
Speciation
Spermatogenesis
Stomata
Telomere
Thermoregulation
Totipotent
Transcription Factor
Transpiration
Trophic Level
Tumour Suppressor Gene
Ultrafiltration
Vacuole
Vasoconstriction
Water Potential
Xylem
Zona Pellucida
Zygote

…and 1,400+ more terms in the full app, with flashcards for every one.

IB Biology Revision FAQ

Everything students commonly ask about revising for IB Biology.

What topics are covered in IB Biology?

IB Biology is organised into four overarching themes: Unity and Diversity (A topics — water, nucleic acids, cell structure, viruses, classification, evolution, conservation), Form and Function (B topics — carbohydrates, lipids, proteins, membranes, organelles, gas exchange, transport, muscles), Interaction and Interdependence (C topics — enzymes, respiration, photosynthesis, signalling, immunity, populations, energy transfer), and Continuity and Change (D topics — DNA replication, protein synthesis, mutations, cell division, gene expression, reproduction, inheritance, homeostasis, natural selection, climate change).

HL students study all SL content plus additional topics: A2.1 Origins of Cells, A2.3 Viruses, A3.2 Cladistics, B3.3 Muscles, and C2.1 Chemical Signalling.

What is the difference between IB Biology SL and HL?

IB Biology HL covers all SL content plus additional Higher Level-only topics. HL students study Origins of Cells (how life began, the Miller-Urey experiment), detailed Virus biology, Cladistics and molecular classification, Muscles and the sliding filament theory, and Chemical Signalling including hormone cascades and G-proteins.

HL students also complete approximately 90 additional teaching hours compared to SL, and the HL Paper 3 contains HL-only questions. The HL course is significantly more demanding in terms of content depth and mathematical treatment.

How many terms do I need to know for IB Biology?

The 2025 IB Biology syllabus includes over 1,500 defined key terms across all topics. In practice, the mark scheme rewards precise use of terminology — for example, writing "partially permeable" rather than "selectively permeable" can affect marks in some questions.

Cramly covers every term from the syllabus, organized by topic, so you can focus your revision on areas where your knowledge is weakest.

What is the best revision strategy for IB Biology?

The most effective strategies for IB Biology are:

Active recall — test yourself on definitions and concepts rather than rereading notes. Flashcards, past paper questions, and games like Cramly's Recall mode force your brain to retrieve information, which strengthens memory far more than passive revision.

Spaced repetition — review material at increasing intervals (1 day, 3 days, 1 week, 2 weeks). Cramly's flashcard algorithm handles the scheduling automatically.

Past papers — IB Biology mark schemes are precise. Practicing on past papers trains you to use the exact phrasing the examiners expect.

Diagram practice — the examiners frequently ask you to label or draw diagrams (the nephron, the sarcomere, the chloroplast, etc.). Drawing these from memory is one of the best ways to test understanding.

When should I start revising for IB Biology?

Ideally, start building vocabulary from the beginning of the course — even 10 minutes a day of flashcard practice across the full two years is far more effective than intensive cramming in the final weeks.

If your exams are approaching, prioritise: (1) topics you haven't revised at all, (2) definitions and terminology for mark scheme accuracy, (3) past paper practice for Paper 1 MCQs and Paper 2 structured questions.

Is Cramly free for IB Biology?

Yes — Cramly is completely free. There is no premium tier, no paywall, and no credit card required. All flashcards, games, and progress tracking are available at no cost.

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